Crystal structure of human CPSF73 catalytic segment in complex with compound 1

Crystal structure of human CPSF73 catalytic segment in complex with compound 1 Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ... Authors: Huang, J, Tong, L. Deposit date: 2023-06-02 Release date: 2023-11-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol, 31, 2024人类切割与多聚腺苷酸化特异性因子73（Cleavage and polyadenylation specificity factor 73, CPSF73）催化片段与化合物1结合的晶体结构 描述符：3-[7,7-二(羟基)-8-氧杂-7-硼杂二环[4.3.0]壬-1,3,5-三烯-5-基]-N-[3-(4-乙酰苯基)苯基]丙酰胺、氯离子、切割与多聚腺苷酸化特异性因子亚基3（Cleavage and polyadenylation specificity factor subunit 3, CPSF3）…… 作者：Huang J, Tong L 存放日期：2023-06-02 发布日期：2023-11-08 最后修改日期：2024-01-31 实验方法：X射线衍射（分辨率1.7 Å） 引用文献：抗癌苯并氧硼类化合物通过直接抑制CPSF3阻断前信使RNA加工。《Cell Chem Biol》，31卷，2024年