Effective antiretroviral therapy, anal high-risk human papillomavirus, anal intraepithelial neoplasia and anal cancer: a systematic review and meta-analysis

This dataset contains data evaluating the association of antiretroviral therapy, HIV plasma viral load and contemporary and nadir CD4+ T-cell count (exposures) and the following outcomes: outcomes: anal HR-HPV prevalence, incidence and persistence; cytology- or histology-confirmed anal squamous intraepithelial lesions [SIL]/anal intraepithelial neoplasia [AIN] prevalence, incidence, progression or regression, and anal cancer incidence among people living with HIV (PLHIV). It includes raw data for outcomes and exposure, and the crude effect estimate, and the adjusted effect estimate provided in the published material, in additional to information on the any adjustment for confounding, where available.本数据集旨在评估抗反转录病毒治疗（antiretroviral therapy）、HIV血浆病毒载量、当前CD4+ T细胞计数及最低CD4+ T细胞计数作为暴露因素，与下述结局的关联：肛门高危型人乳头瘤病毒（anal HR-HPV）的患病率、发病率及持续感染率；经细胞学或组织学确诊的肛门鳞状上皮内病变（SIL）/肛门上皮内瘤变（AIN）的患病率、发病率、进展或消退情况，以及艾滋病病毒感染者（PLHIV）的肛门癌发病率。本数据集包含结局与暴露因素的原始数据、已发表文献中提供的粗效应量与校正效应量，此外还包含可用的混杂因素校正相关信息。