CryoEM structure of PI3Kalpha
收藏Protein Data Bank Japan2025-05-28 更新2026-06-30 收录
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CryoEM structure of PI3Kalpha Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Authors: Valverde, R, Shi, H, Holliday, M. Deposit date: 2023-08-15 Release date: 2023-11-15 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3K alpha Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discov, 14, 2024
创建时间：
2023-08-15
