官方服务:
资源简介:
ChIP-Seq reads from naive CD8+ T-cells from Kmt2d KO and Kmt2d WT mice. Cells from each group were either a) unstimulated or b) stimulated with anti-CD3/CD28.
应用场景:
创建时间:
2022-12-31
相关数据集
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T-cells
DNA hypomethylating agents (HMAs) induce Type I/III interferon signaling through dsRNA-mediated viral mimicry in cancer cells. Yet, the direct effects of HMAs in immune cells remains less clear. Here,
NIAID Data Ecosystem50
Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells. Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem40
Analysis of transcriptome changes in Kmt2d deletion in cardiac mesoderm, anterior heart field precursors and cardiomyocytes
KMT2D is required in the cardiac mesoderm, anterior heart field precursors and cardiomyocytes. Kmt2d deletion in cardiac mesoderm (Mesp1Cre) is embryonic lethal at E10.5 and mutants have hypoplastic h
Alliance of Genome Resources10
Genome-wide transcriptome profiling of wild-type and Kmt2d-deficient ATDC5 differentiated chondrocytes and undifferentiated mesenchymal cells. Genome-wide transcriptome profiling of wild-type and Kmt2d-deficient ATDC5 differentiated chondrocytes and undifferentiated mesenchymal cells
We performed genome-wide transcriptome profiling in stable Kmt2d-/- (bi-allelic deletion of the catalytic SET domain) and Kmt2d+/+ ATDC5 chondrocyte cell lines 7 days after induction of differentiatio
NIAID Data Ecosystem50
Tcf1/Lef1 transcription factors and CD8 T cell identity [ChIP-seq]
Determine genome-wide binding locations by Tcf1 in naive CD8+ T cells Splenocytes were harvested from hCD2-Cre, Rosa26-lsl-GFP, Tcf1/Lef1 wild-type or double floxed mice, and sorted for GFP+TCRbeta+ n
NIAID Data Ecosystem10



