CRISPR screen of B cell receptor-controlled adhesion
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP346679
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资源简介：
To find novel kinases involved in the B cell receptor - integrin axis, we performed a CRISPR screen with the kinome-centered Brunello library in an adhesion assay, in which Namalwa cells were stimulated with anti-IgM or PMA, and allowed to adhere to fibronectin-coated wells. This pathway is important for retention of CLL, MCL, and other lymphoma cells in lymphoid tissues.
创建时间：
2022-03-10
