Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273

Protein Data Bank Japan2023-12-06 更新2026-03-21 收录

下载链接：

https://pdbj.org/mine/summary/4jvv

下载链接

链接失效反馈

官方服务：

资源简介：

Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273 Descriptor: evolved variant of the computationally designed serine hydrolase Authors: Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2013-03-26 Release date: 2013-04-24 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.288 Å) Cite: Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014

计算设计丝氨酸水解酶OSH55.4_H1的进化变体的晶体结构，该变体与二异丙基氟磷酸（diisopropyl fluorophosphate, DFP）共价结合，隶属于东北结构基因组学联盟（NESG）靶标OR273。描述：经进化改造的计算设计丝氨酸水解酶作者：Kuzin, A、Lew, S、Rajagopalan, S、Seetharaman, J、Tong, S、Everett, J.K、Acton, T.B、Baker, D、Montelione, G.T、Tong, L、Hunt, J.F、东北结构基因组学联盟（NESG）存档日期：2013-03-26 发布日期：2013-04-24 最后修改日期：2023-12-06 实验方法：X射线衍射（分辨率2.288埃）引用文献：以原子级精度设计激活型含丝氨酸催化三联体，《自然·化学生物学》（Nat.Chem.Biol.），第10卷，2014年

创建时间：

2013-03-26