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Heat stress, low mango yields and inconsistent fruit quality are main challenges for growers. Recently, licorice-root extract (LRE) has been utilized to enhance vegetative growth, yield, and tolerance abiotic stresses fruit trees. Potassium sorbate (PS) also plays a significant role in various physiological and biochemical processes that are essential for mango growth, quality and abiotic stress tolerance. This work aimed to elucidate the effects of foliar sprays containing (LRE) and (PS) on the growth, yield, fruit quality, total chlorophyll content, and antioxidant enzymes of 'Osteen' mango trees. The mango trees were sprayed with (LRE) at 0, 2, 4 and 6g/l and PS 0, 1, 2, and 3mM. In mid-May, the mango trees were sprayed with a foliar solution, followed by monthly applications until one month before harvest. The results showed that trees with the highest concentration (6 g/L) of LRE exhibited the maximum leaf area, followed by those treated with the highest concentration (3 mM) of PS. Application of LRE and PS to Osteen mango trees significantly enhanced fruit weight, Number of fruits.tree^-1, yield (kg/tree), yield increasing%, and reduced No. of sun-burned fruits compared to the control. LRE and PS foliar sprays to Osteen mango trees significantly enhanced fruit total soluble solids ˚Brix, TSS/acid ratio, and Vitamin C content compared to the control. Meanwhile, Total acidity percentage in 'Osteen' mango fruits significantly decreased after both LRE and PS foliar sprays. 'Osteen' mango trees showed a significant increase in leaf area, total chlorophyll content, total pigments, and carotenoids of leaf. Our results suggest that foliar sprays containing LRE and PS significantly improved growth parameters, yield, fruit quality, antioxidant content, and total pigment concentration in ‘Osteen’ mango trees. Moreover, the most effective treatments were 3mM KS and 6g/L LRE. LRE and PS foliar spray caused a significant increase in yield percentage by 305.77%, and 232.44%, in the first season, and 242.55%, 232.44% in the second season, respectively.