Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 1 sticky bases and 3' terminal phosphates.

Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 1 sticky bases and 3' terminal phosphates. Descriptor: DNA (5'-D(GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*A)-3'), DNA(5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-')|, MAGNESIUM ION, ... Authors: Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. Deposit date: 2023-07-20 Release date: 2023-08-02 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Tuning Chemical DNA Ligation within DNA Crystals and Protein-DNA Cocrystals. Acs Nanosci Au, 4, 2024

本数据集为复制起始蛋白（Replication Initiator Protein）REPE54与对称扩展双链体（31聚体）形成的等网状互穿共晶体；该双链体包含同源REPE54序列、一段额外的富G-C序列，带有1个粘性碱基及3'端磷酸基团。序列标注：DNA (5'-D(GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*A)-3')、DNA(5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-')|，镁离子等。作者：Orun A.R、Shields E.T、Shrestha R、Slaughter C.K、Snow C.D。提交日期：2023年7月20日，发布日期：2023年8月2日，最后更新日期：2024年11月6日。实验方法：X射线衍射（2.54埃）。引用文献：《DNA晶体与蛋白-DNA共晶体内的DNA连接化学调控》（Tuning Chemical DNA Ligation within DNA Crystals and Protein-DNA Cocrystals），ACS Nanosci Au，第4卷，2024年