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Figshare2022-02-25 更新2026-04-08 收录
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24 male SD rats were randomly divided into normal control group,PPARγ agonist group (rosiglitazone 10 mg/kg.d), PPARγ inhibitor group(GW9662,1mg/kg·d)and hypoxia injury group, with six rats in each group. The normal control group without any treatment,the other three groups were exposed to 7500 m altitude for seven hours of acute hypobaric hypoxia. The mRNA and protein expressions of PPARγ, SOD, IL-1β and renal ET-1 in renal tissue were detected by using RT-qPCR and western blotting. The kidney’s morphology was observed by light microscope and electron microscope.

提供机构:
Zhu, Shi-Qun
创建时间:
2022-02-25
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