Parkinson's Anxiety Network (anxiety-network-pd)

An a priori anxiety network, based on previously reported results in structural and microstructural Parkinson’s disease anxiety literature. This network will be used in a region of interest analysis in a neuroimaging study characterising the microstructural basis of anxiety in early Parkinson's disease. It will be used alongside a High Density Anxiety Network (10.5281/zenodo.17158446). This network was updated in September 2025 and replaced a previous version originally published in November 2024. Following advice from an advisory thesis committee, a systematic review of PD anxiety neuroannatomical literature was conducted to inform the network, replacing a previous narrative review. This resulted in small changes to the annatomical nodes of the network. The update includes the addition of the left inferior frontal gyrus (opercular and triangular part), bilateral medial orbital gyrus, left anteroventral nucleus of the thalamus, bilateral substantia nigra pars compacta and reticulata and ventral tegmental area. The left inferior frontal gyrus pars orbitalis was removed. All other regions remain the same.