CRISPR screen to identify regulators of epigenetic memory in ESC
收藏官方服务：
资源简介：
CRISPR screen to identify regulators of epigenetic memory in ESC
应用场景：
创建时间：
2021-11-23
相关数据集
Transcriptomic analysis of human cybrid cell lines harboring increasing levels of the mitochondrial DNA (mtDNA) 3243A>G mutation
Mitochondria generate signals of adaptation that regulate nuclear genes expression via retrograde signaling. But this phenomenon is complexified when qualitatively different mitochondria and mitochon
NIAID Data Ecosystem110
Dnmt3L-dependent regulation of DNA methylation promotes stem cells differentiation toward primitive germinal cells. Dnmt3L-dependent regulation of DNA methylation promotes stem cells differentiation toward primitive germinal cells
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem40
Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration [P5]
In order to understand if early epigenetic mechanisms instruct the long-term behaviour of neural stem cells (NSCs) and their progeny, we examined the protein Uhrf1 as it is highly expressed in NSCs of
Alliance of Genome Resources10
Data sheet index below 1.
In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
Figshare2022-09-22 更新50
CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function. CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function
Natural killer T cells (NKTs) are a promising platform for cancer immunotherapy, but few genes involved in regulation of NKT therapeutic activity have been identified. To discover regulators of NKT fu
NIAID Data Ecosystem30
