X-ray crystal structure analysis of bovine spleen cathepsin B-CA077 complex

X-ray crystal structure analysis of bovine spleen cathepsin B-CA077 complex Descriptor: BENZYL N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, CATHEPSIN B, GLYCEROL, ... Authors: Watanabe, D. Deposit date: 2006-01-01 Release date: 2006-01-24 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published

牛脾脏组织蛋白酶B（CATHEPSIN B）-CA077复合物的X射线晶体结构分析。描述符：苄基 N-({(2S,3S)-3-[(苄基氨基)羰基]环氧乙烷-2-基}羰基)-L-异亮氨酰-L-脯氨酸酯（BENZYL N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE）、组织蛋白酶B（CATHEPSIN B）、甘油（GLYCEROL）等。作者：Watanabe, D.。提交日期：2006-01-01。发布日期：2006-01-24。最后修改日期：2024-10-30。方法：X射线衍射（X-RAY DIFFRACTION，1.93埃）。引用文献：基于一系列环氧琥珀酰基抑制剂的抑制活性-结合模式关系，通过复合物的X射线晶体结构分析，定量评估组织蛋白酶B各活性亚位点的抑制活性，待发表。