GROVERS DISEASE: ANALYSIS OF A CASE EXHIBITING SIMILARITIES WITH PEMPHIGUS

Grovers disease, also known as benign acantholytic dermatosis or acantholytic dyskeratosis, is a rare dermatosis characterized by a pruritic skin rash on the trunk, arms, and legs. Although the exacr pathogenesis of this disease remains unknown, certain factors such as heat, excessive sweating, sun exposure, and systemic diseases have been implicated in its onset however, it is generally considered to be an inflammatory reaction. Histology of the sample revealed suprabasal acantholysis, which manifested as clefts rather than true blisters, with mild dyskeratosis. These characteristics raised diagnostic uncertainty between Grovers disease and pemphigus vulgaris. However , testing for autoantibodies against intercellular spaces returned negative, confirming the diagnosis of Grovers disease. Due to the possibility of spantaneous regression , treatment options are limited. For cases of moderate and temporary nature, local corticosteroid therapy alone is often sufficient.