Transcriptomic analysis of mRNA expression profiles in the microglia of mouse brains infected with rabies viruses of varying virulence

Rabies is a lethal encephalitis caused by rabies virus (RABV) with a fatality rate near 100% after the onset of clinical symptoms in humans and animals. Microglia are resident immune cells of the central nervous system. Few studies have been conducted on the functional role of microglia in RABV infection. Here, we performed a transcriptomics analysis of mRNA expression profiles in the microglia of mouse brains intracerebrally infected with RABV