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资源简介：
the effect of eIF4E2/GSK3b pathway on p53 dependent transcription
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创建时间：
2020-06-30
相关数据集
Chen et al 2019 "iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition"
Raw Western blot and luciferase assay data to support the experimental results presented in the publication by Chen et al 2019 entitled "iASPP mediates p53 selectivity through a modular mechanism fine
NIAID Data Ecosystem90
Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq). Homo sapiens
GRO-seq of HCT116 cells treated with Nutlin to activate p53 Overall design: HCT116 cells were treated with Nutlin or DMSO for 1 hour
NIAID Data Ecosystem40
Genomewide analysis of the human p53 transcriptional network unveils a lncRNA tumor suppressor signature (expression)
We report the application of high-throughput sequencing to performed the p53 regulated trancriptome in HCT116 colon cancer cells treated with the DNA damage 5FU. To study the direct targets of p53 we
NIAID Data Ecosystem30
Targeted citrullination enables p53 binding to non-canonical sites [165]
TP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Activation of p53 results in highly specific transcriptional responses, but the regu
NIAID Data Ecosystem50
Gene expression in human lymphoblastoid cell-line GM12878 in response to doxorubicin treatment. Homo sapiens
To determine if induced p53 binding is associated with gene expression in genome-wide. We examined mRNA levels with the Affymetrix Human Exon 1.0 ST platform in human lymphoblastoid GM12878 cells trea
NIAID Data Ecosystem40
