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Altered bone marrow myelopoiesis contributes to kidney injury [RNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277474
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The objectives of this study were to characterize bone marrow alteration in the context of kidney disease. Mobilized apheresis products were collected from de-identified, healthy donors. Isolated CD34+ HSPCs were cultured in myeloid expansion medium for 10 days with or without TNFα supplement. For bulk ATAC and RNA sequencing, CD14+ monocytic cells were further isolated at day 10.
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2024-09-19
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