PHGDH covalently linked to oridonin

PHGDH covalently linked to oridonin Descriptor: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, CHLORIDE ION, D-3-phosphoglycerate dehydrogenase, ... Authors: Sun, Q, Lei, Y. Deposit date: 2020-11-25 Release date: 2022-02-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors. Cell.Mol.Life Sci., 79, 2021与冬凌草甲素（oridonin）共价结合的PHGDH（D-3-磷酸甘油酸脱氢酶，D-3-phosphoglycerate dehydrogenase）描述符：(1β,6β,7β,8α,9β,10α,13α,14R,16β)-1,6,7,14-四羟基-7,20-环氧贝壳松烷-15-酮、氯离子、D-3-磷酸甘油酸脱氢酶等。作者：孙Q、雷Y。提交日期：2020-11-25；发布日期：2022-02-02；最后修改日期：2024-11-13。实验方法：X射线衍射（分辨率1.7埃）。引用文献：《通过PHGDH抑制剂研究揭示的PHGDH生物物理与生化特性》，《Cellular and Molecular Life Sciences》（缩写：Cell. Mol. Life Sci.），第79卷，2021年。