Background Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to i
The reported incidence of osteoporosis is lower in countries in which the Mediterranean diet predominates, and this apparent relationship may be mediated by the phenolic compounds present in olive oil
To investigate the role of LINE-1 in bone regeneration, we delivered synthetic L1 RNA to mesenchymal stem cells (MSC), from osteoporotic patients, induced to osteogenic differentiation. Overall design
Neural crest cells (NCCs) are multipotent stem cells with a remarkable ability to differentiate into multiple cell lineages, including osteoblasts and chondrocytes. NCCs contribute to the majority of
The transcriptome of Mouse embryo osteoblast 3T3-E1 cells was sequenced. The experimental group was 3T3-E1 cells transfected with lentivirus containing mir-18a mimics. The control group was 3T3-E1 cel