Processed Nanopore sequencing outputs for KMS12-PE multiple myeloma cell lines (part 1)

This dataset contains raw Nanopore sequencing reads for samples of multiple myeloma cell lines(KMS12-PE) treated with demethylating agents. The data are provided in FASTQ format and were generated using the Oxford Nanopore Technologies sequencing platform. Sequencing libraries were prepared using the Oxford Nanopore Technologies (ONTs) Native Barcoding Kit 96 V14 (SQK-NBD114.96) (Oxford Nanopore Technologies, Oxford, United Kingdom), and VAHTS TGS DNA Library Prep Kit for ONT (Vazyme, Nanjing, China) following the manufacturer´s protocol with modifications. For sequencing, 5 μL of the library was loaded onto an R10.4.1 flow cell (FLO-PRO114) and sequenced on the PromethION platform (Oxford Nanopore Technologies, Oxford, United Kingdom). These reads can be used for analysis of DNA methylation and hydroxymethylation.