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Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

NIAID Data Ecosystem2026-05-02 收录

银屑病转录组学

植物药抗银屑病机制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP571303 数据链接链接失效反馈

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资源简介：

The purpose of this study was to investigate the therapeutic mechanism of the anti-psoriatic effect of P. clypearia by transcriptomics technology.

应用场景：

创建时间：

2025-03-20

巨噬细胞极化

银屑病转录组学

To determine the transcriptional profile associated with macrophage polarization to M1 or M2, we cultured macrophages derived from monocytes for 7 days and treated them with IFNg, IL-4, TNF, LPS, and

NIAID Data Ecosystem100

Combined miRNA-mRNA transcriptional profiling in the human skin [miRNA_PSOR]

皮肤病

银屑病转录组学

mRNA and miRNA transcription changes during epidermal differentiation and between lesional psoriatic skin and normal skin were analyzed 4 skin biopsies of lesional psoriatic skin and 4 healthy control

NIAID Data Ecosystem60

Transcription profiling of human affected and unaffected skin of 4 psoriatic patients and normal skin of 3 psoriasis free individuals to reveal a complex regulation of molecular stress and immune gene responses

银屑病转录组学

免疫相关基因表达

ChEBI2007-09-20 更新10

Gene expression profiling in psoriatic lesional and non-lesional skin [Set 1]. Homo sapiens

银屑病转录组学

皮肤病变基因表达

To explore the psoriasis phenotype, we characterize gene expression in lesional and non-lesional skin from psoriasis patients. Overall design: We extracted total RNA from 5mm punch biopsies taken from

NIAID Data Ecosystem60

Transcriptome analysis of Psoriasis

银屑病转录组学

治疗反应生物标志物

Newly diagnosed psoriatic patients were recruited into this study (total 12 patients. Initially 16 patients were enrolled but only 12 of these patients had complied IRB protocol). These patients were

NIAID Data Ecosystem20

Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

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