Calculated properties of anticomplement proteins.

Amino-acid sequences were deduced from the sequenced open reading frames. Indicated values were calculated from deduced amino-acid sequences using online programs at CBS and EBI (see text). Signal peptide cleavage sites are indicated by the position of the residues between which the cleavages were predicted to occur. (a) I. scapularis sequence [25]. (b) I. pacificus sequence [30]. (c) after removal of the predicted signal peptide at the most likely cleavage position (see text). aa, amino-acids; MW, molecular weight; kDa, kiloDaltons; pI, isoelectric point; N-gly., number of predicted N-glycosylation sites; O-gly., number of predicted O-glycosylation sites.