RNA-seq profile of stimulated Tregs containing co-receptor signaling domain variant chimeric antigen receptors (CARs).
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介：
Initial CAR therapies were designed and tested in conventional T cells, however several recent reports indicate that CAR Tregs may be effective in solid organ transplant or hematopoietic stem cell transplant. Since Tregs have different activation requirements, we sought to characterize the transcriptional profile of Tregs that were transduced with second-generation CARs containing various co-receptor signaling moieties to determine which bestows Tregs with the most desireable properties.
提供机构：
University of British Columbia
创建时间：
2022-02-20
