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RNA-seq of Lin-CD34+ cord-blood cells overexpressing PLAG1-S or firefly Luciferase [OE]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181976
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资源简介:
To characterize transcriptional changes associated with gain of the transcription factor PLAG1-S that could contribute to transient ex vivo expansion of human cord-blood (CB) derived HSC we performed RNA-seq of 2 pools of Lin-CD34+ CB cells 72 hours following lentiviral introduction of ectopic PLAG1-S or firefly Luciferase (control). Lin-CD34+ samples from 2 biologically distinct pools of CB were transduced to overexpress PLAG1-S or firefly Luciferase (control), and 72 hours following viral introduction transduction marker positive cells were FACS-isolated for bulk RNA-seq.
创建时间:
2022-12-01
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