Single Cell Transcriptomics of iPSC derived neurons under genetic and toxic stressors. Single Cell Transcriptomics of iPSC derived neurons under genetic and toxic stressors

Human iPSC derived dopaminergic neurons were characterized using unbiased single cell transcriptomics. Then study the genetic effect of the A-syn A53T mutation along with oxidative and ER stress induced by rotenone and tunicamycin respectively.