Impact of different PrEP scenarios in Botswana, Nyanza and Southern India.

aAll PrEP scenarios started in 2012. ‘Low’ and ‘high’ refer to PrEP effectiveness and PrEP coverage; ‘sex workers’ and ‘sex workers/clients’ refer to the different target groups.
bAdult population size in 2012.
cNumber of PrEP pills per 100,000 uninfected adult person years needed in the period 2013–2022 in scenarios in which condom use was unchanged.
dNumber of averted HIV infections per 100,000 uninfected adult person years in the period 2013–2022.
e‘Same’ means unchanged condom use during PrEP: 50% in Botswana/Nyanza and 90% in Southern India; ‘Less’ means condom substitution during PrEP (i.e. less condom use): 35% in Botswana/Nyanza and 75% in Southern India; ‘More’ means condom addition during PrEP (i.e. more condom use): 62.5% in Botswana/Nyanza and 92.5% in Southern India.