Expression profile alteration of lncRNA and their target genes in patients with aortic dissection

Aortic dissection (AD) is a cardiovascular emergency resulted from blood flows into vessel wall, with high mortality in early stage. Due to the vital pathological mechanism for AD occurrence has not been clarified, and no effective ways to prevent and diagnose AD’s process. In this study, we determine the lncRNA expression profile in aortic dissection group and control group. The key lncRNAs were screen out by using microarray analysis in defferent group. The experiment is divided into two groups: HT as control group, AD as study group. Then perform lncRNAs chips by Arraystar Human lncRNAs chip (Arraystar).