OsteoclastPFARescue_PercentViabilityData.tab

This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoclastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure (CONT) during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated RAW264.7, RANKL-differentiated osteoclasts. "MEDIA" control percent viability was mildly but significantly lower than the viability of the combined zoledronate (ZOL) + PFA vehicles (VEHS) control; consequently, the vehicles had a positive effect on viability. All other percent viabilities for the other conditions were expressed relative to the ZOL + PFA VEHS' viability. N=6.