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HCFC2 needed for IRF1- and IRF2-dependent Tlr3 transcription, and for survival during viral infections

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100436
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IRF1 and IRF2 are transcription factors for interferon stimulated genes. HCFC2 facillitates their assoication with DNA targets and maintains the proper transcitpion of target genes. IRF2 assoicated DNA sequences were recovered from mouse embryonic fibroblasts (MEFs), comparing cells of wildtype and Hcfc2 knockout
创建时间:
2021-07-25
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