Aging Mouse Brain Epigenetic
收藏aws亚马逊开源数据集2025-12-27 收录
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https://registry.opendata.aws/salk-aging-mouse-brain-epigeneti
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资源简介:
Aging is a major risk factor for neurodegenerative diseases, yet underlying epigenetic mechanisms remain unclear. Here, we generated a comprehensive single-nucleus cell atlas of brain aging across multiple brain regions, comprising 132,551 single-cell methylomes and 72,666 joint chromatin conformation-methylome nuclei. Integration with companion transcriptomic and chromatin accessibility data yielded a cross-modality taxonomy of 36 major cell types.
提供机构:
Salk Institute



