Karyotype analysis of S. cerevisiae chromosome replacement lines - alpha-type cells

The S. cerevisiae hybrid karyotypes were analyzed by array-CGH to identify small regions of duplication or homeologous chromosomal exchange occurring during the strain construction.研究人员通过阵列比较基因组杂交（array-CGH）技术，对酿酒酵母（S. cerevisiae）的杂交核型展开分析，以鉴定菌株构建过程中出现的小型染色体重复区域或部分同源染色体交换事件。