Table 5 in Acute toxicity and antiproliferative and procoagulant activities of fractions derived from Thymus satureioides of the Moroccan High Atlas

Table 5 Effect of the CE and organic fractions from T. satureioides in ear oedema model induced by croton oil.
GroupEar oedema rate (%)2 h4 h6 h8 h10 hControl28.89 ± 0.7541.31 ± 0.7941.30 ± 0.6047.39 ± 0.5037.32 ± 0.67Crude extract11.04 ± 0.2723.05 ± 0,4840.13 ± 1.2833.33 ± 1.36**41.86 ± 0.22**Dichloromethane fraction20.22 ± 4.97*28.26 ± 4.01**23.07 ± 8.72*23.75 ± 3.9412.80 ± 5.78**E. acetate fraction21.99 ± 0.95*30.09 ± 0.46 **15.97 ± 7.01**12.27 ± 5.935.79 ± 6.63***Methanol fraction30.28 ± 1.0839.70 ± 0.7940.51 ± 0.4335.74 ± 2.27*31.24 ± 9.27Aqueous fraction30.38 ± 4.6640.81 ± 1.0146.56 ± 1.5945.32 ± 0.1838.46 ± 5.70Indomethacin34.23 ± 0.95*33.33 ± 1.36**17.59 ± 0.7215.51 ± 0.64***11.57 ± 0.07***
The animals (n = 6) were treated with CE and fractions from T.satureioides at 1 mg/ear.Indomethacin was used as a positive control (600 μg/ear). The differences between treatment and control were tested using ANOVA followed by Turkey's test. Values are mean ± SEM, (n = 6), where * P <.05, ** P <.01 and *** P <.001 compared to control.