five

Human Fen1 in complex with an N-hydroxyurea compound

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Human Fen1 in complex with an N-hydroxyurea compound Descriptor: 1-[(2S)-2,3-dihydro-1,4-benzodioxin-2-ylmethyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione, FLAP ENDONUCLEASE 1, MAGNESIUM ION Authors: Exell, J.C, Thompson, M.J, Finger, L.D, Shaw, S.K, Abbott, W.M, McWhirter, C, Debreczeni, J.E, Jones, C.D, Nissink, J.W.M, Ward, T.A, Sioberg, C.W.L, Molina, D.M, Durant, S.T, Grasby, J.A. Deposit date: 2016-02-03 Release date: 2016-08-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Cellular Active N-Hydroxyurea Fen1 Inhibitors Block Substrate Entry to the Active Site Nat.Chem.Biol., 12, 2016
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2016-02-03
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