Drugs and other xenobiotics are not only secreted/reabsorbed by the renal proximal tubule epithelial cells (RPTEC) but may also adversely impact kidney function. In vitro models that can afford predic

NIAID Data Ecosystem40

A Gene Expression Profile in the Kidney After Cisplatin Treatment

药物肾毒性

转录组生物标志物

Clinical use of a major cancer chemotherapeutic agent, cisplatin, is restricted to dose-limiting renal toxicity. A transcriptomic approach enabled us to extract putative molecules including Pleckstrin

NIAID Data Ecosystem30

DataSheet1_Bismuth Reduces Cisplatin-Induced Nephrotoxicity Via Enhancing Glutathione Conjugation and Vesicular Transport.pdf

药物肾毒性

金属药物相互作用

Bismuth drugs have long been used against gastrointestinal diseases, especially the gastric infection of Helicobacter pylori. Cisplatin is a widely used anticancer drug that tends to accumulate at ren

NIAID Data Ecosystem40

Supplementary Material for: Hospital-Acquired Acute Kidney Injury in Older Patients: Clinical Characteristics and Drug Analysis

急性肾损伤

药物肾毒性

Background: Information on older patients with hospital-acquired acute kidney injury (HA-AKI) and use of drugs is limited. Aim: This study aimed to assess the clinical characteristics, drug uses, and

NIAID Data Ecosystem40

Renal morphology.

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