Homo sapiens Genome sequencing. Homo sapiens
收藏NIAID Data Ecosystem2026-03-10 收录
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资源简介：
specificity of genome editing using cas9 variants in iPSC
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创建时间：
2018-07-19
相关数据集
Whole genome Sequencing of Cas9-mediated corrected iPSCs.
Confirmation of the nuclease acivities at the On- and Off-target sites. Genomic DNA was extracted using G-DEXTM IIc genomic DNA extraction kit (iNtRON Biotech) according to manufacturer’s protocols fr
NIAID Data Ecosystem50
CRISPR transduction of iPS cells
Genome engineering using CRISPR/Cas9 technology enables simple, efficient and precise genomic modifications in human cells. Conventional immortalized cell lines can be easily edited or screened using
NIAID Data Ecosystem40
Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient iPSCs [RNA-seq]. Homo sapiens
We compared the epigenetic status of the mutant and disease-free iPSCs at the whole genome level. Whole epigenome profiling based on trimethylated H3K4 (H3K4me3) showed concordant epigenetic remodelin
NIAID Data Ecosystem20
Additional file 9 of Clinical exome analysis and targeted gene repair of the c.1354dupT variant in iPSC lines from patients with PROM1-related retinopathies exhibiting diverse phenotypes
Supplementary file 9: Sequencing data from IRD2’ daughter.
Figshare2024-08-18 更新40
Homo sapiens Exome. Homo sapiens
In this study, we sought to determine the requirements for targeted integration of a corrective DNA construct into the endogenous WAS locus of WAS-patient derived iPS cells. Our goal was to demonstrat
NIAID Data Ecosystem30
