Deciphering the proteomic profile of the parasite Fasciola hepatica during host migration reveals new insights into early-stage infection

The project presents an in vivo mouse model coupled with quantitative SWATH-MS proteomics to study the early stages of Fasciola hepatica migration, focusing on the parasite's passage through the intestinal barrier to peritoneum(24 hours post-infection) and migration to the liver parenchyma (8 days post-infection). This approach aims to assess the proteomic changes in the parasite during these critical stages of infection.