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The NGS data was used to analyze the frequency of base editing in yeast
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创建时间：
2018-12-13
相关数据集
Increase base editing efficiency and product variety through fusion of Cas9 nickase to cytosine and adenosine deaminases
Base editors, which are created through fusion of Cas9 nickase to either cytidine or adenine deaminase, efficiently catalyze site-specific nucleotide conversions with minimal indel rates1, 2. However,
NIAID Data Ecosystem50
A-T to G-C base editing efficiency at targeted gene sites in HEK293T cell line
A-T to G-C base editing efficiency at targeted gene sites in HEK293T cells using the dCas12f-ABE design or the Cas12f-ABE design. Found that the total A-T to G-C conversion efficiency of Circular gRNA
NIAID Data Ecosystem30
GO: A functional reporter system to identify and enrich base editing activity
This study developed tools for enriching base editing events in mouse and human cell lines
NIAID Data Ecosystem20
Programmable RNA base editing with a single engineered protein
Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro
NIAID Data Ecosystem40
dual gRNA system achieve efficient C-to-T&G-to-A,A-to-G&T-to-C base editing
dual gRNA system achieve efficient C-to-T&G-to-A,A-to-G&T-to-C base editing
NIAID Data Ecosystem30
