Differentiation of lncRNAs expression during the polarization macrophages

To determine lncRNAs transcribed during the polarization of macrophages, we have employed whole genome microarray expression profiling as a discovery platform to identify lncRNAs expression in mouse primary bone marrow derived macrophages (BMDMs) treated with M1 (lipopolysaccharide, LPS) and M2 (IL-4) stimulators. The changed lncRNA expression in mouse BMDMs untreated (M/Ctrl) , or treated with LPS 6hours, IL-4 24 hours, respectively. Three independent experiments were performed at each treat (M, LPS, IL-4).