Analyses of the real sequence data.

In the Dallas sample, three genes (ABCA1, APOA1, and LCAT) were sequenced in two groups, each of which contained 128 individuals. A total of 29 non-synonymous variants were identified, but only 18 variants were available for analysis. 16 of these 18 variants were exclusive to the case group, and the remaining 2 were exclusive to the control group. In the Canada sample, the same three genes were sequenced in two groups containing 155 and 108 individuals. Of the 23 variants that were available for analysis, 21 were exclusive to the case group and the remaining 2 were exclusive to the control group.