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PdgfrB signaling impairs skeletal muscle regeneration

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Genetically deleting PdgfrB in mature myocytes enhances skeletal muscle regeneration and fusion capability whereas activating PdgfrB inhibits it. Comparative gene expression profile analysis of RNA-Seq data between 2 month old control, moygenin specific PdgfrB knock out, and myogenin specific PdgfrB constitutively active male mice

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