Atypical chromatin structure of immune-related genes expressed in chicken erythrocytes [RNA-seq]

Transcriptional regulation is impacted by multiple layers of genome organization. Here, we report that immune genes were associated with H3K4me3 and H3K27ac. In conjunction with next-generation DNA, RNA sequencing, chromatin immunoprecipitation-DNA sequencing and FAIRE sequencing, we identified the active chromosomal compartments and determined their structural signatures in relation to expression levels. Examination of gene expression in 6C2 line (a transformed chicken erythrocyte precursor cell line).