首页/数据集/MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I. MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I. MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I

NIAID Data Ecosystem2026-03-13 收录

阿尔茨海默病机制

坏死性凋亡调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA800730 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-01-26

阿尔茨海默病机制

神经元基因调控分析

IPA of upstream regulators of genes preferentially expressed in neurons. Table S8 notes the upstream regulators of genes that are downregulated in Alzheimerâ s disease and upregulated by candesartan

Figshare2016-12-16 更新60

Whole transcriptome analysis of brain hippocampal tissue from SAMP8 mice and rat primary neurons treated with the Alzheimer’s disease drug candidate CAD031

阿尔茨海默病机制

衰老模型转录组学

Alzheimer’s disease (AD) drug discovery has rarely been addressed in the context of aging even though sporadic AD accounts for 99% of the cases. Phenotypic screens based upon old age-associated brain

Alliance of Genome Resources40

ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism

阿尔茨海默病机制

线粒体代谢

ABCA7 loss-of-function variants are associated with increased risk of Alzheimer's disease (AD). Using ABCA7 knockout human iPSC models generated with CRISPR/Cas9, we investigated the impacts of ABCA7

NIAID Data Ecosystem20

Table_1_Protect Effects of Seafood-Derived Plasmalogens Against Amyloid-Beta (1–42) Induced Toxicity via Modulating the Transcripts Related to Endocytosis, Autophagy, Apoptosis, Neurotransmitter Release and Synaptic Transmission in SH-SY5Y Cells.DOC

阿尔茨海默病机制

神经药物靶点

To investigate the underlying mechanisms of decreased plasmalogens (Pls) levels in neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and differentiated human SH-S

NIAID Data Ecosystem50

mouse fecal bolus Raw sequence reads. mouse fecal bolus

消化道微生物组

阿尔茨海默病机制

In this study, we used two human amyloid precursor protein (hAPP) knock-in (KI) mouse models to investigate the potential associations between AD pathology, the gut microbiome and brain DNA methylatio

NIAID Data Ecosystem40

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I. MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease I

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