PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000515a

PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000515a Descriptor: 1-[(3S,3aS,8bS)-5-fluoro-3-(hydroxymethyl)-2,3,3a,8b-tetrahydro-1H-[1]benzofuro[3,2-b]pyrrol-1-yl]ethan-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2018-08-30 Release date: 2018-10-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.703 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018

PanDDA分析小组存档——与化合物_FMOOA000515a结合的蛋白酪氨酸磷酸酶1B（PTP1B）晶体结构。相关描述组分包括：1-[(3S,3aS,8bS)-5-氟-3-(羟甲基)-2,3,3a,8b-四氢-1H-[1]苯并呋喃并[3,2-b]吡咯-1-基]乙-1-酮、2-氨基-2-羟甲基丙烷-1,3-二醇、非受体1型酪氨酸蛋白磷酸酶。作者为Keedy, D.A.、Hill, Z.B.、Biel, J.T.、Kang, E.、Rettenmaier, T.J.、Brandao-Neto, J.、von Delft, F.、Wells, J.A.、Fraser, J.S.。存档日期：2018-08-30；发布日期：2018-10-10；最后修改日期：2024-03-06。实验方法：X射线衍射（分辨率1.703埃）。引用文献：《通过多温度晶体学、片段筛选与共价锚定技术解析PTP1B的扩展变构网络》，发表于Elife, 7, 2018。