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BRD4 in complex with FragLite15

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Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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BRD4 in complex with FragLite15 Descriptor: 4-bromanyl-2-methoxy-pyridine, GLYCEROL, Isoform C of Bromodomain-containing protein 4 Authors: Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. Deposit date: 2022-03-22 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022

BRD4与FragLite15的复合物 结构描述:4-溴-2-甲氧基吡啶、甘油、含溴结构域蛋白4亚型C(Bromodomain-containing protein 4 Isoform C);作者:Turberville, S、Martin, M.P、Hope, I、Noble, M.E.M.;提交日期:2022-03-22;发布日期:2022-11-23;最后修改日期:2024-01-31;实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.1 Å;引用文献:《利用FragLites与PepLites及卤代探针解析溴结构域BRD4与ATAD2的配体相互作用——类药与肽样分子相互作用的卤代探针》,*Journal of Medicinal Chemistry*(缩写J.Med.Chem.),2022年,第65卷

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2022-03-22
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