Application of the Illumina MethylationEPIC on small amount of fragmentized HCT116 genomic DNA

Cell-free DNA is generally in fragments around 200 bp. Genomic DNA from HCT116 cell is sonicated to around 200 bp to mimic cell-free DNA. This is a control assay to test the sensitivity of Infinium methylationEPIC array for low amount of fragmentized DNA. The genomic DNA was extracted from HCT116 cell and sonicated to fragment around 200 bp. DNA methylation was detected by Infinium methylationEPIC array.