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Characterization of The Functional Role of PEAK1 and PEAK3 Pseudokinases

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Monash University Figshare2026-02-11 更新2026-07-07 收录
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The three pseudokinases PEAK1, PEAK2 and the recently identified PEAK3 constitute the PEAK family. Both PEAK1 and PEAK2 function as scaffolds to regulate cell proliferation, migration and invasion. PEAK3 is a novel pseudokinase, whose signalling pathways and function remain poorly characterized. In this thesis, the role of PEAK1 in mammary gland development and PEAK3 signalling mechanisms and function were characterized.

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2022-04-15
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