We differentiated naïve CD4 T cells isolated from FoxP3-eGFP mice into inducible regulatory T cells in presence or absence of CPI-1205. Differentiated regulatory T cells were then sorted by flow cytom
To analyze gene expression in in regulatory T cell precursors that develop in the absence of a functional Foxp3 protein as compared to that of normal regulatory T cells Keywords: Cell type comparison
CD4+Foxp3+ regulatory T cells (Tregs) are essential for maintaining immune tolerance, and selective expansion of Tregs via TNFR2 signaling represents a promising therapeutic approach for autoimmune an
