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dCas9 activation of RP11-326A19.4 phase 2

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE142097
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Transfection experiments aimed at understanding the impact of upregulating lncRNA RP11-326A19.4 on the transcriptome; follow-up of GSE132451 HEK293T cells were transfected with CRISPRa (dCas9-VPR) alongside either 2 gRNA expression constructs targeting the promoter region (CG4:-334 and CG6:-505 relative to TSS) of a lncRNA (RP11-326A19.4) or tracrRNA only for 48 h. Sample RNAs were then analyzed on human HuGene-2_0-ST (Affymetrix).
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2024-01-29
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