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Silver(I)-Catalyzed Tandem Sigamatropic Rearrangement/1,3‑H Shift/6π Aza-electrocyclization of N‑Propargylic Hydrazones: A Mild Synthetic Route to 1,6-Dihydropyridazines

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Figshare2016-05-02 更新2026-04-29 收录
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A highly efficient AgOTf catalyzed [3,3] sigmatropic rearrangement/1,3-H shift/6π aza-electrocyclization cascade reaction of N-propargylic hydrazones has been developed. This method provides a new mild synthetic route to various polysubstituted 1,6-dihydro­pyridazines including the 3-CF3-substituted ones with high selectivity.

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2016-05-02
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