Molecular consequences of proprotein convertase 1/3 inhibition in macrophages for application to cancer immunotherapy: a proteomic study

Data from ProteomeXchange, PXD ID: PXD001984. File: KO_LPS1.mzml. Published as part of Mol Cell Proteomics. 2015 Sep 1 . From the Abstract: {{i}} ... Here, we investigated the intracellular impact of the down-regulation of the proprotein convertase 1/3 in NR8383 macrophages. A complete proteomic study of secretomes and intracellular proteins was undertaken and revealed that inhibition of proprotein convertase 1/3 orient macrophages toward an M1 activated phenotype ... {{/i}}