Additional file 1 of The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases

Additional file 1: Table S1. Transformation of traits in BioBank Japan and taxa in GNHS. Table S2. Required effect size (beta) to reach 80% of power in GNHS cohort. Table S3 Heritability of taxa, enterotype and alpha diversity. Table S4. Significant genetic correlations of gut microbiome and metabolic traits. Table S5. Significant associations of all taxa with SNPs identified in the discovery stage before adjustment (p<5e-8). Table S6. Replication of genetic variants associated with taxa. Table S7. Replication of genetic variants associated with beta diversity. Table S8. Replication of genetic variants associated with alpha diversity. Table S9. Lead SNPs used to construct polygenic scores. Table S10. MR analysis of gut microbiota on traits and diseases. Table S11. MR analysis of diseases on gut microbiota features. Table S12. Spearman’s correlation of certain taxa and complex diseases. Table S13. Spearman’s correlation of gut microbiota on genus level and characteristics.